Description: Advances in Host-directed Therapies Against Tuberculosis, Hardcover by Karakousis, Petros C. (EDT); Hafner, Richard (EDT); Gennaro, Maria Laura (EDT), ISBN 3030569047, ISBN-13 9783030569044, Brand New, Free shipping in the US This book discusses specific immune cell regulatory pathway(s), immune cell types, or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT). The pathways/mechanisms investigated are either protective – thus calling for pathway/factor enhancing drugs – or maladaptive – thus calling for pathway/factor inhibitory drugs. Discovery and development (pre-clinical and clinical) of candidate HDT agents will also be elucidated, as well as approaches for HDT of other diseases. The benefit to the reader will derive from learning about the biology of multiple host pathways involved in health and disease, how these pathways are disrupted or dysregulated during tuberculosis, and which druggable targets exist in these pathways. This book provides the reader with a roadmap of current and future directions of HDT against tuberculosis. Since the host pathways/factors involved in protective or maladaptive responses to tuberculosis are not disease-specific, information learned from the context of tuberculosis likely will be relevant to other infectious and non-infectious diseases.
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Book Title: Advances in Host-directed Therapies Against Tuberculosis
Number of Pages: Xiii, 332 Pages
Language: English
Publication Name: Advances in Host-Directed Therapies Against Tuberculosis
Publisher: Springer International Publishing A&G
Subject: Immunology, Internal Medicine, Diseases
Publication Year: 2020
Item Weight: 24.3 Oz
Type: Textbook
Author: Richard Hafner
Item Length: 9.3 in
Subject Area: Medical
Item Width: 6.1 in
Format: Hardcover
