Cytochrome P450: Structure, Mechanism, and Biochemistry by Paul R. Ortiz de Mont

Description: Cytochrome P450 by Paul R. Ortiz de Montellano Estimated delivery 3-12 business days Format Paperback Condition Brand New Description This authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as the microbial, plant, and insect systems, and the second exclusively focusing on mammalian systems.Volume 1 begins with an exploration of the biophysics and mechanistic enzymology of cytochrome P450 enzymes, with a discussion of the structures of P450 enzymes and their electron donor partners, the mechanisms of oxygen activation and substrate oxidation, and the approaches and nature of cytochrome P450 inhibition. Two more chapters discuss the nature and roles of cytochrome P450 enzymes in microbes, plants and insects, and an eighth chapter is a survey of the potential utility of P450 enzymes in biotechnology. The first chapter of Volume 2 examines the roles of P450 enzymes in mammals, mainly humans. Four further chapters then deal with the genetic and hormonal regulation of P450 enzymes and their specific roles in the processing of sterols and lipids. Cytochrome P450: Structure, Mechanism, and Biochemistry is a key resource for scientists, professors, and students interested in fields as diverse as biochemistry, chemistry, biophysics, molecular biology, pharmacology and toxicology. Author Biography Paul R. Ortiz de Montellano received his PhD in bioorganic chemistry from Harvard University, Cambridge, MA. After postdoctoral work as a North Atlantic Treaty Organization Fellow in ZÜrich, Switzerland, and a stint with Syntex in Mexico City and Palo Alto, California, he joined the faculty of the University of California in San Francisco, where he is currently Professor, Vice-chair of the Department of Pharmaceutical Chemistry, and Associate Dean for Research of the School of Pharmacy. His research interests center on the structure, mechanism, inhibition, and biochemistry of hemoproteins, including the cytochrome P450 enzymes. He has received the B.B. Brodie Award in Drug Metabolism from the American Society of Pharmacology and Experimental Therapeutics, the R.T. Williams Distinguished Scientific Achievement Award from the International Society for the Study of Xenobiotics, and the Ernest H. Volwiler Research Achievement Award from the American Association of Colleges of Pharmacy. Details ISBN 3319374370 ISBN-13 9783319374376 Title Cytochrome P450 Author Paul R. Ortiz de Montellano Format Paperback Year 2016 Pages 912 Edition 4th Publisher Springer International Publishing AG GE_Item_ID:137771681; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

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End Time: 2024-09-28T02:47:46.000Z

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