Dubois' Lupus Erythematosus and Related Syndromes by Daniel J. Wallace Paperback

Description: FREE SHIPPING UK WIDE Dubois' Lupus Erythematosus and Related Syndromes by Daniel J. Wallace, Bevra Hahn For more than 50 years, Dubois Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the 10th edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. Its an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes.Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education.Includes significant new content throughout: a new chapter on the endocrine system and hormones; newly distinct chapters on the heart and lung; new content on social disparities in lupus, clinical presentation of nephritis, and pulmonary hypertension; a new concluding chapter on future directions in the field; new basic science coverage of the microbiome, autoinflammatory, and monogenic lupus; and new coverage of diversity, inclusion, gender, compliance, and adherence.Offers a fresh perspective from two new associate editors and many new authors with representation from 30 countries.Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients.Discusses the clinical management of related disorders such as Sjogrens syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS).Presents the knowledge and expertise of international contributors to provide new global perspectives on manifestations, diagnosis, and treatment.Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, new and improved figures, and schematic diagrams throughout.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date. FORMAT Paperback CONDITION Brand New Author Biography Daniel J Wallace MD, FACP, MACR is a board-certified internist and rheumatologist. A Clinical Professor of Medicine at the David Geffen School of Medicine at UCLA, he is the Associate Director of the Rheumatology Fellowship Program at Cedars-Sinai Medical Center, where he also serves on the Board of Governors. Dr. Wallace has authored nearly 450 peer reviewed manuscripts, 30 book chapters, eight textbooks (on lupus, osteoarthritis, Sjogrens syndrome and fibromyalgia) and his practice includes caring for 2,000 lupus patients, the largest lupus cohort in the United States. Dr Wallace is co-chair of the Lupus Industry Council of the Lupus Research Alliance, past chair of the Lupus Foundation of America, and has served on the Board of Directors of the United Scleroderma Foundation and the Medical Advisory Board of the Sjogrens Syndrome Foundation. He has been Chief of Rheumatology at the City of Hope and Cedars-Sinai Medical Center, and chairman of the Research and Education Foundation of the American College of Rheumatology. Dr. Hahn received her MD from the Johns Hopkins University School of Medicine, where she later trained in Rheumatology. She trained in internal medicine at Washington University in St. Louis. Dr. Hahn heads research groups that do basic studies in the immune abnormalities that cause systemic lupus erythematosus (SLE) and is developing interventions that help restore the immune response to normal. She also heads a group that studies clinical problems in patients with SLE, including accelerated atherosclerosis and potential new therapies (clinical trials). In addition, Dr. Hahn provides clinical consultations for patients with rheumatic diseases, particularly SLE. She also teaches Rheumatology and heads the administration of the Division of Rheumatology, which has 25 full-time faculty, 8 fellows and several undergraduate students, medical students, PhD students, postdoctoral trainees, and an administrative staff. Table of Contents SECTION 1 What Is Lupus?1 History of Lupus2 Definition and Classification of Lupus and Lupus-Related Disorders3 The Epidemiology of LupusSECTION 2 Pathogenesis4 Overview of Lupus Pathogenesis5 Genetics of SLE6 Single Gene Defects and Autoinflammation: Relation to Lupus7 Epigenetics of Lupus8 The Role of the Environment and Microbiome in Lupus9 The Innate Immune System in SLE10 B Cells and Generation of Antibodies11 T cells12 Immunoregulatory Cells and Networks in Lupus13 Cytokines in Lupus14 Metabolic Control of Immunopathogenesis in Systemic Lupus Erythematosus15 Animal Models of Systemic Lupus Erythematosus (SLE)SECTION 3 Mechanisms of Tissue Injury16 Abnormalities in Clearance of Immune Complexes and Dying Cells in Lupus17 Complement and Systemic Lupus Erythematosus18 Apoptosis and Inflammatory Forms of Cell Death19 Tissue Damage in Lupus: Free Radicals and Fibrosis20 Lupus Nephritis21 Pathogenesis of Accelerated Atherosclerosis and Vascular Injury in Systemic Lupus Erythematosus22 Pathogenesis of Cutaneous Lupus23 Pathogenesis of Neuropsychiatric Lupus24 Pathogenesis of Sjögren SyndromeSECTION 4 Autoantibodies25 Antinuclear Antibodies, Antibodies to DNA, Histones, and Nucleosomes26 Antibodies Against Extractable Nuclear Antigens(RNP, Sm, SS-A/Ro, and SS-B/La)27 Other Autoantibodies: Antibodies to C1q, Lipoprotein, and Endothelial Cells28 Pathogenesis of Antiphospholipid Antibody Syndrome29 Drug-Induced LupusSECTION 5 Clinical Aspects of Lupus Erythematosus30 Overview and Clinical Presentation31 Skin Disease in Cutaneous Lupus Erythematosus32 The Musculoskeletal System and Bone Metabolism33 Lupus and the Cardiovascular System34 Pulmonary Manifestations of Systemic Lupus Erythematosus35 Lupus and the Nervous System: Clinical Presentation, Diagnosis, and Treatment36 Gastrointestinal and Hepatic Manifestations37 The Gut Microbiome and Lupus Pathogenesis38 Hematologic and Lymphoid Abnormalities in SLE39 Neonatal Lupus: Pathogenesis and Clinical Approaches40 Pregnancy and Reproductive Health Issues in Systemic Lupus Erythematosus41 Systemic Lupus Erythematosus in Childhood and Adolescence42 Clinical Aspects of Antiphospholipid Syndrome43 Lupus and Infections44 Ocular, Aural, and Oral Manifestations of Lupus45 Clinical Aspects of Sjögrens Disease46 Clinical Presentations of Lupus in the Kidney and Urogenital System47 The Endocrine System and Hormones in LupusSECTION 6 Assessment of Lupus48 Clinical Application of Serologic Tests, Serum Protein Abnormalities, and Other Laboratory Tests in Systemic Lupus Erythematosus49 Differential Diagnosis and Disease Associations50 Incomplete Lupus, Undifferentiated Connective Tissue Disease, and Mixed Connective Tissue Disease51 Clinical Markers, Metrics, Indices, and Clinical TrialsSECTION 7 Management of Lupus52 Principles of Therapy, Local Measures, and NSAIDs53 Antimalarial Medications54 Systemic Glucocorticoid Therapy for SLE55 Immunosuppressive Drug Therapy56 Complementary and Integrative Health Approaches57 Specialized and Niche Therapies58 Adjunctive and Preventive Measures59 Management of Cutaneous Lupus Erythematosus60 Targeted Therapies in SLE61 Management of Lupus Nephritis62 Management of Sjögren Disease SyndromeSECTION 8 Outcomes63 Socioeconomics, Disparities, and Disability64 Prognosis and Mortality of Systemic Lupus Erythematosus65 Future Directions: Therapeutics66 Expanding the Opportunities to Effectively Treat Patients: Clinical ConsiderationsIndex Review "This book is a comprehensive and up-to-date review of Lupus Erythematosus and related syndromes written by over 100 experts in the field. The previous edition was published in 2018." ©Doodys Review Service, 2024, Massoud Mahmoudi, DO, PhD (University of California San Francisco) Details ISBN0323932320 Author Bevra Hahn Pages 816 Publisher Elsevier - Health Sciences Division Edition Description 10th edition Year 2024 Edition 10th ISBN-13 9780323932325 Imprint Elsevier - Health Sciences Division Place of Publication Philadelphia Country of Publication United States Replaces 9780323479271 Alternative 9780323933490 Edited by Bevra Hahn Audience Professional & Vocational Format Paperback DEWEY 616.772 NZ Release Date 2024-02-25 AU Release Date 2024-02-25 Publication Date 2024-03-27 US Release Date 2024-03-27 ISBN-10 0323932320 UK Release Date 2024-03-27 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! 30 DAY RETURN POLICY No questions asked, 30 day returns! 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