Description: High-Throughput Lead Optimization in Drug Discovery, Paperback by Kshirsagar, Tushar (EDT), ISBN 0367387719, ISBN-13 9780367387716, Brand New, Free P&P in the UK
A single source on parallel synthesis for lead optimization, this book features real-world examples and contributions from well-known scientists. It explores the shift to conducting parallel lead optimization in-house while outsourcing most of the screening libraries synthesis. With more than 15 case studies that encompass a range of biological targets for application in different therapeutic areas, the text contains examples of solid and solution-phase techniques for the synthesis of directed libraries. The authors explain the design principles they used to direct the choice of templates and diversity elements and they explore how this technology, when applied to library design, can speed up drug discovery.
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Book Title: High-Throughput Lead Optimization in Drug Discovery
Number of Pages: 256 Pages
Publication Name: High-Throughput Lead Optimization in Drug Discovery
Language: English
Publisher: Taylor & Francis LTD
Item Height: 254 mm
Subject: Medicine, Engineering & Technology
Publication Year: 2019
Type: Textbook
Item Weight: 499 g
Author: Tushar Kshirsagar
Item Width: 178 mm
Series: Critical Reviews in Combinatorial Chemistry
Format: Paperback