Description: Mitochondrial cytopathies are mutations in the inherited maternal mitochondrial genome, or the nuclear DNA-mutation. Mitochondrial respiratory chain disorders (RCD) are a group of genetically and clinically heterogeneous diseases, due to the fact that protein components of the respiratory chain are encoded by both mitochondrial and nuclear genomes and are essential in all cells. In addition, the biogenesis, structure and function of mitochondria, including DNA replication, transcription, and translation, all require nuclear encoded genes. Since mitochondria are present in every cell, every tissue, mitochondrial disorder usually affects multiple organs.
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EAN: 9781489992413
UPC: 9781489992413
ISBN: 9781489992413
MPN: N/A
Item Length: 23.4 cm
Number of Pages: 372 Pages
Language: English
Publication Name: Mitochondrial Disorders Caused by Nuclear Genes
Publisher: Springer-Verlag New York Inc.
Publication Year: 2014
Subject: Medicine, Biology
Item Height: 235 mm
Item Weight: 5796 g
Type: Textbook
Author: Lee-Jun C. Wong
Item Width: 155 mm
Format: Paperback