Description: Principles for Modelling Dose-Response for the Risk Assessment of Chemicals, Paperback by Not Available (na), Not Available (na), ISBN 9241572396, ISBN-13 9789241572392, Like New Used, Free shipping in the US This volume is part of the ongoing review of the underlying scientific bases for decision-making in chemical risk assessment by International Programme on Chemical Safety. It involves specific consideration of the area of dose–response assessment in the evaluation of information from toxicological studies in animals and from human clinical and epidemiological studies. It covers toxicants with threshold effects and those for which there may be no practical threshold, such as substances that are genotoxic and carcinogenic. The discussions are concerned with that subset of cause–effect relationships commonly referred to as dose–response models, which are typically used to characterize the biological effects of intentional (. drugs and nutrients) and unintentional (. contaminants) exposure to chemicals. This report is intended primarily to provide descriptive guidance for risk assessors in using dose–response modelling in hazard characterization. It will also provide mathematical modellers with an appreciation of issues to be considered when modelling in the context of the risk assessment process. Risk managers will be able to obtain a general understanding of the applications and limitations of dose–response modelling. For both risk assessors and risk managers, some considerations for communicating the results of risk assessments that use dose–response modelling are presented.
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Book Title: Principles for Modelling Dose-Response for the Risk Assessment of
Number of Pages: 124 Pages
Publication Name: Principles for Modelling Dose-Response for the Risk Assessment of Chemicals
Language: English
Publisher: World Industries Health Organization
Publication Year: 2009
Subject: Chemistry / Environmental (See Also Environmental Science), Toxicology, Public Health, Health Risk Assessment, Environmental / General
Item Weight: 8.6 Oz
Type: Textbook
Author: Ipcs
Item Length: 9.2 in
Subject Area: Technology & Engineering, Science, Medical
Series: Public Health Ser.
Item Width: 6.2 in
Format: Trade Paperback
