Description: Real-time Monitoring of Cancer Cell Metabolism for Drug Testing, Paperback by Alborzinia, Hamed, ISBN 3658101601, ISBN-13 9783658101602, Brand New, Free shipping in the US Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines; (ii) a detailed timeline of the metabolic response to cisplatin treatment and clear detection of the time span between start of cisplatin treatment and onset of cell death, which reflects the time required for the underlying molecular mechanisms of cell fate decision; (iii) direct functional measurement of the biological activity of a key regulatory protein of cellular metabolism following the kinetic change in respiration upon SIRT3 overexpression; and (iv) the time-resolved impact of several organometallic compounds on cell metabolism and cell morphology, including unexpected and not yet understood highly significant and specific effects on cell-cell interaction and adhesion.
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Book Title: Real-time Monitoring of Cancer Cell Metabolism for Drug Testing
Number of Pages: Xiii, 153 Pages
Language: English
Publication Name: Real-Time Monitoring of Cancer Cell Metabolism for Drug Testing
Publisher: Springer Fachmedien Wiesbaden Gmbh
Subject: Chemistry / Clinical, Oncology, Pharmacology
Publication Year: 2015
Type: Textbook
Item Weight: 79.5 Oz
Subject Area: Science, Medical
Author: Hamed Alborzinia
Item Length: 8.3 in
Item Width: 5.8 in
Format: Trade Paperback