Description: Further DetailsTitle: Cytochrome P450 2D6Condition: NewFormat: PaperbackSubtitle: Structure, Function, Regulation and PolymorphismEAN: 9780367658595ISBN: 9780367658595Publisher: CRC PressRelease Date: 09/30/2020Description: Cytochromes are proteins that catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singlehandedly metabolizes about 25% of all medications in the human liver. Cytochrome P450 2D6: Structure, Function, Regulation, and Polymorphism reviews the current knowledge of CYP2D6 as well as the maturing body of evidence indicating its significance to clinical and pharmacological researchers and practitioners. This book focuses on the critical role CYP2D6 plays in the human liver. It examines the genetic, epigenetic, physiological, pathological, and structural factors of the gene that govern the highly variable metabolism of a number of drugs in clinical use. It highlights the impact of the functional roles of CYP2D6 on clinical practice and drug development and also discusses implications for precise medicine, strategies to avoid adverse drug reactions, and paths for future research. Cytochrome P450 2D6 is a unique, valuable book focusing on a single but immensely powerful human gene. It provides the first single source of comprehensive information on CYP2D6 that serves as an important reference for medical, biomedical, pharmaceutical, and nursing researchers, practitioners, and students.Language: EnglishCountry/Region of Manufacture: GBItem Height: 280mmItem Length: 210mmItem Weight: 453gAuthor: Shufeng ZhouGenre: MedicineTopic: Science Nature & MathISBN-10: 0367658593Type: Internal MedicineEdition: 1stRelease Year: 2020 Missing Information?Please contact us if any details are missing and where possible we will add the information to our listing.
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Format: Paperback
Book Title: Cytochrome P450 2D6
Publication Name: Cytochrome P450 2D6
Title: Cytochrome P450 2D6
Subtitle: Structure, Function, Regulation and Polymorphism
EAN: 9780367658595
ISBN: 9780367658595
Publisher: CRC Press
Release Date: 09/30/2020
Release Year: 2020
Language: English
Country/Region of Manufacture: GB
Item Height: 280mm
Item Length: 210mm
Item Weight: 453g
Author: Shufeng Zhou
Genre: Medicine
Topic: Science Nature & Math
ISBN-10: 0367658593
Type: Internal Medicine
Edition: 1st
