Description: Stochastic Narrow Escape in Molecular and Cellular Biology by David Holcman, Zeev Schuss This book covers recent developments in the non-standard asymptotics of the mathematical narrow escape problem in stochastic theory, as well as applications of the narrow escape problem in cell biology. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description This book covers recent developments in the non-standard asymptotics of the mathematical narrow escape problem in stochastic theory, as well as applications of the narrow escape problem in cell biology. The first part of the book concentrates on mathematical methods, including advanced asymptotic methods in partial equations, and is aimed primarily at applied mathematicians and theoretical physicists who are interested in biological applications. The second part of the book is intended for computational biologists, theoretical chemists, biochemists, biophysicists, and physiologists. It includes a summary of output formulas from the mathematical portion of the book and concentrates on their applications in modeling specific problems in theoretical molecular and cellular biology.Critical biological processes, such as synaptic plasticity and transmission, activation of genes by transcription factors, or double-strained DNA break repair, are controlled by diffusion in structures that have both large and small spatial scales. These may be small binding sites inside or on the surface of the cell, or narrow passages between subcellular compartments. The great disparity in spatial scales is the key to controlling cell function by structure. This volume reports recent progress on resolving analytical and numerical difficulties in extracting properties from experimental data, biophysical models, and from Brownian dynamics simulations of diffusion in multi-scale structures. Back Cover This book covers recent developments in the non-standard asymptotics of the mathematical narrow escape problem in stochastic theory, as well as applications of the narrow escape problem in cell biology. The first part of the book concentrates on mathematical methods, including advanced asymptotic methods in partial equations, and is aimed primarily at applied mathematicians and theoretical physicists who are interested in biological applications. The second part of the book is intended for computational biologists, theoretical chemists, biochemists, biophysicists, and physiologists. It includes a summary of output formulas from the mathematical portion of the book and concentrates on their applications in modeling specific problems in theoretical molecular and cellular biology. Critical biological processes, such as synaptic plasticity and transmission, activation of genes by transcription factors, or double-strained DNA break repair, are controlled by diffusion in structures that have both large and small spatial scales. These may be small binding sites inside or on the surface of the cell, or narrow passages between subcellular compartments. The great disparity in spatial scales is the key to controlling cell function by structure. This volume reports recent progress on resolving analytical and numerical difficulties in extracting properties from experimental data, biophysical models, and from Brownian dynamics simulations of diffusion in multi-scale structures. Table of Contents Elementary Theory of Stochastic Narrow Escape.- Special Asymptotics for Stochastic Narrow Escape.- NET in Molecular and Cellular Biology.- Applications to Cellular Biology and Simulations.- Determination of Features from Super-Resolution Data.- Markov Models for Stochastic Chemical Reactions.- Random Search with Switching.- Narrow Escape in Other Cellular Processes.- Modeling the Early Steps of Viral Infection in Cells. Feature Shows how to implement models and numerical methods Provides the latest techniques in applied mathematics for cellular microdomains Takes a quantitative approach in cellular biology and open questions (signaling in virus trafficking, growth cone dynamics, DNA breaks, and many others) Details ISBN1493941232 Author Zeev Schuss Language English ISBN-10 1493941232 ISBN-13 9781493941230 Media Book Format Paperback DEWEY 530.1 Series Biological and Medical Physics, Biomedical Engineering Year 2016 Publication Date 2016-10-25 Imprint Springer-Verlag New York Inc. Subtitle Analysis and Applications Place of Publication New York Country of Publication United States Short Title Stochastic Narrow Escape in Molecular and Cellular Biology UK Release Date 2016-10-25 AU Release Date 2016-10-25 NZ Release Date 2016-10-25 US Release Date 2016-10-25 Illustrations 38 Illustrations, color; 38 Illustrations, black and white; XIX, 259 p. 76 illus., 38 illus. in color. Edited by Christopher E. Swide Birth 1974 Affiliation European University Viadrina, Germany Position journalist Qualifications Ph.D. Pages 259 Publisher Springer-Verlag New York Inc. Edition Description Softcover reprint of the original 1st ed. 2015 Alternative 9781493931026 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:130977871;
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ISBN-13: 9781493941230
Book Title: Stochastic Narrow Escape in Molecular and Cellular Biology
Item Height: 235 mm
Item Width: 155 mm
Author: David Holcman, Zeev Schuss
Publication Name: Stochastic Narrow Escape in Molecular and Cellular Biology: Analysis and Applications
Format: Paperback
Language: English
Publisher: Springer-Verlag New York Inc.
Subject: Biology, Mathematics, Physics
Publication Year: 2016
Type: Textbook
Item Weight: 4277 g
Number of Pages: 259 Pages
